Rare diseases · Sign or symptom

Humoral immunodeficiency

HP:0005363

What it means

A general term referring to a defect in immunity resulting from impaired antibody production.

If possible it is preferable to use a precise description of the observed manifestations leading to the inference of humoral immunodeficiency.

Rare diseases that can present with this5

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Humoral immunodeficiency

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.