Rare diseases · Sign or symptom
High maternal circulating chorionic gonadotropin concentration
HP:0011433
What it means
An abnormally high concentration of maternal serum human chorionic gonadotropin as compared to normal values for gestational-age.
Reduced levels of alpha-fetoprotein can be seen in some fetal disorders such as Down syndrome.
Rare diseases that can present with this2
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: High maternal serum chorionic gonadotropin · High maternal serum hCG
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.