Rare diseases · Sign or symptom
Heterochromia iridis
Different colored eyes
HP:0001100
What it means
Heterochromia iridis is a difference in the color of the iris in the two eyes.
Rare diseases that can present with this23
Very common80–99%
3Common30–79%
8The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Different coloured eyes · Heterochromia irides
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.