Rare diseases · Sign or symptom
Hemiparesis
Weakness of one side of body
HP:0001269
What it means
Loss of strength in the arm, leg, and sometimes face on one side of the body. Hemiplegia refers to a complete loss of strength, whereas hemiparesis refers to an incomplete loss of strength.
Rare diseases that can present with this53
Very common80–99%
5Common30–79%
17- Arterial dissection-lentiginosis syndrome
- Autoimmune hemolytic anemia-autoimmune thrombocytopenia-primary immunodeficiency syndrome due to TPP2 deficiency
- Behçet disease
- Classic glucose transporter type 1 deficiency syndrome
- Familial cerebral saccular aneurysm
- Familial or sporadic hemiplegic migraine
- Focal facial dermal dysplasia type IV
- Hemiparkinsonism-hemiatrophy syndrome
- Isolated focal cortical dysplasia
- MELAS
- Polymicrogyria due to TUBB2B mutation
- Primary angiitis of the central nervous system
- Rasmussen syndrome
- Schizencephaly
- Sneddon syndrome
- Unilateral polymicrogyria
- X-linked adrenoleukodystrophy
Sometimes5–29%
25- Acute disseminated encephalomyelitis
- Adams-Oliver syndrome
- African trypanosomiasis
- Amoebiasis due to free-living amoebae
- Bilateral frontal polymicrogyria
- CACH syndrome
- Cerebral autosomal recessive arteriopathy-subcortical infarcts-leukoencephalopathy
- Craniofaciofrontodigital syndrome
and 17 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.