Rare diseases · Sign or symptom
Hand tremor
Tremor of hand
HP:0002378
What it means
An unintentional, oscillating to-and-fro muscle movement affecting the hand.
Rare diseases that can present with this24
Very common80–99%
5Common30–79%
10- 9p13microdeletion syndrome
- Autosomal dominant Charcot-Marie-Tooth disease type 2A2
- Autosomal recessive spastic paraplegia type 69
- Autosomal recessive spastic paraplegia type 70
- Autosomal recessive spastic paraplegia type 71
- Charcot-Marie-Tooth disease type 1F
- Congenital glucokinase-related hyperinsulinism
- Progressive essential tremor-speech impairment-facial dysmorphism-intellectual disability-abnormal behavior syndrome
- X-linked Charcot-Marie-Tooth disease type 2
- X-linked dystonia-parkinsonism
Sometimes5–29%
8- Autosomal recessive cerebellar ataxia due to STUB1 deficiency
- Autosomal spastic paraplegia type 18
- Cranio-cervical dystonia with laryngeal and upper-limb involvement
- Intellectual disability-balding-patella luxation-acromicria syndrome
- Kjellin syndrome
- PHIP-related behavioral problems-intellectual disability-obesity-dysmorphic features syndrome
- Recessive intellectual disability-motor dysfunction-multiple joint contractures syndrome
- Spinocerebellar ataxia type 27A
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Tremor of hands · tremors in hands
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.