Rare diseases · Sign or symptom

Gingival hyperkeratosis

HP:0000222

What it means

Hyperkeratosis of the gingiva.

The condition results in the teeth being partially or totally engulfed by keratinized gingiva, causing esthetic and functional problems.

Rare diseases that can present with this1

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Hyperkeratosis, gingival

Gingival hyperkeratosis

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.