Rare diseases · Sign or symptom

Gastrointestinal ulcer

HP:0034274

What it means

A deep defect in the esophageal, gastric, duodenal or intestinal wall involving the entire mucosal thickness and penetrating through the muscularis mucosae.

Gastrointestinal ulcers result from the tissue necrosis triggered by mucosal ischemia, ree radical formation and cessation of nutrient delivery, all caused by vascular and microvascular injury such as thrombi, constriction, or other occlusion.

Part of the broader category

Gastrointestinal ulcer

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.