Rare diseases · Sign or symptom

Flexion contracture of the 2nd toe

HP:0010327

What it means

One or more bent (flexed) joints of the second toe that cannot be straightened actively or passively.

Rare diseases that can present with this1

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Joint contractures of the 2nd toe

Flexion contracture of the 2nd toe

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.