Rare diseases · Sign or symptom
Extremely elevated creatine kinase
HP:0030235
What it means
An increased creatine kinase level more than 50X above the upper normal level.
Rare diseases that can present with this2
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Extremely elevated CPK · Extremely elevated creatine phosphokinase · Extremely elevated phospho-CK serum level · Extremely elevated serum CK level · Extremely high CPK level
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.