Rare diseases · Sign or symptom

ERG: Reduced dark-adapted b-wave amplitude

HP:0007984

What it means

A dark-adapted bright flash electroretinogram in which the b-wave that is of markedly lower amplitude than the associated a-wave.

Flashes will elicit an a-wave with an initial negative deflection followed by a b-wave with positive deflection. This feature refers to a reduction in the amplitude primarily of the b-wave.

Rare diseases that can present with this5

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Electronegative ERG · Electroretinogram: reduced b-wave amplitude · Reduced amplitude of dark-adapted bright flash electroretinogram b-wave · Reduced electroretinogram rod b-wave · Reduced ERG amplitude of b-wave

ERG: Reduced dark-adapted b-wave amplitude

Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.

Start free with Eleplan

This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.