Rare diseases · Sign or symptom

Epiretinal membrane

HP:0100014

What it means

An epiretinal membrane is a thin sheet of fibrous tissue on the surface of the retina along the inner limiting membrane. It appears as a greyish semi-translucent avascular membrane over the internal limiting membrane (ILM) on the surface of the retina.

If the epiretinal membrane is localized in the macula, it can cause disturbances of vision.

Rare diseases that can present with this9

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Cellophane maculopathy · Epiretinal membranes · Macular pucker · Premacular fibrosis · Surface wrinkling retinopathy

Epiretinal membrane

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.