Rare diseases · Sign or symptom
Elevated circulating haptoglobin concentration
HP:0020180
What it means
The concentration of haptoglobin in the blood circulation is above the upper limit of normal.
Haptoglobin is an acute-phase reactant whose levels can become elevated in the presence of infection and inflammation.
Rare diseases that can present with this2
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Elevated haptoglobin concentration · Elevated haptoglobin level · Elevated haptoglobin level in blood · Increased haptoglobin concentration · Increased haptoglobin level · Increased haptoglobin level in blood
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.