Rare diseases · Sign or symptom

Elevated circulating beta-2-microglobulin concentration

HP:0025346

What it means

The concentration of beta-2-microglobulin in the blood circulation is above the upper limit of normal.

Rare diseases that can present with this1

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Elevated beta-2-microglobulin concentration · Elevated beta-2-microglobulin level · Elevated beta-2-microglobulin level in blood · Elevated circulating beta-2-microglobulin level · Increased beta-2-microglobulin concentration · Increased beta-2-microglobulin level · Increased beta-2-microglobulin level in blood

Elevated circulating beta-2-microglobulin…

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.