Rare diseases · Sign or symptom
Developmental stagnation
HP:0007281
What it means
A cessation of the development of a child in the areas of motor skills, speech and language, cognitive skills, and social and/or emotional skills.
Rare diseases that can present with this7
Common30–79%
5- 3-phosphoglycerate dehydrogenase deficiency, infantile/juvenile form
- Infantile neurovisceral acid sphingomyelinase deficiency
- RARS-related autosomal recessive hypomyelinating leukodystrophy
- Short stature-advanced bone age-early-onset osteoarthritis syndrome
- X-linked intellectual disability-plagiocephaly syndrome
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Developmental arrest
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.