Decreased serum leptin

What it means

A decreased concentration of leptin in the blood.

Leptin is an adipocyte-secreted hormone with a key role in energy homeostasis.

Rare diseases that can present with this7

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Reduced circulating leptin level