Decreased number of large peripheral myelinated nerve fibers

What it means

A reduced number of large myelinated nerve fibers.

This finding can be demonstrated by nerve biopsy.

Rare diseases that can present with this7

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Decreased number of large peripheral myelinated nerve fibres · Depletion of large myelinated fibers · Depletion of large myelinated fibres · Loss of large myelinated fibers · Loss of large myelinated fibres · Loss of larger myelinated nerve fibers · Loss of larger myelinated nerve fibres