Rare diseases · Sign or symptom

Decreased circulating iron concentration

HP:0040303

What it means

The concentration of iron cation in the blood circulation is below the lower limit of normal.

Rare diseases that can present with this6

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Decreased iron cation concentration · Decreased iron cation level · Decreased iron cation level in blood · Decreased serum iron · Hypoferremia · Low serum iron · Reduced iron cation concentration · Reduced iron cation level

Decreased circulating iron concentration

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.