Rare diseases · Sign or symptom

Decreased circulating dehydroepiandrosterone-sulfate concentration

HP:0031215

What it means

A reduced concentration of dehydroepiandrosterone-sulfate in the blood.

DHEA is transformed into DHEA-S by sulfation at the C3beta position by sulfotransferase SULT2A1.

Rare diseases that can present with this1

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Decreased circulating dehydroepiandrosterone-sulfate level

Decreased circulating…

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.