Rare diseases · Sign or symptom

Decreased circulating copper concentration

Copper deficiency

HP:0011967

What it means

The concentration of copper cation in the blood circulation is below the lower limit of normal.

Rare diseases that can present with this5

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Decreased copper cation concentration · Decreased copper cation level · Decreased copper cation level in blood · Hypocupremia · Reduced copper cation concentration · Reduced copper cation level · Reduced copper cation level in blood · Reduced serum copper

Decreased circulating copper concentration

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.