Rare diseases · Sign or symptom
Decreased circulating alpha-1-antitrypsin concentration
HP:0032025
What it means
The concentration of alpha-1-antitrypsin in the blood circulation is below the lower limit of normal.
Rare diseases that can present with this1
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Decreased alpha-1-antitrypsin concentration · Decreased alpha-1-antitrypsin level · Decreased alpha-1-antitrypsin level in blood · Reduced alpha-1-antitrypsin concentration · Reduced alpha-1-antitrypsin level · Reduced alpha-1-antitrypsin level in blood · Reduced serum alpha-1-antitrypsin
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.