Rare diseases · Sign or symptom
Decreased circulating alkaline phosphatase activity
Decreased serum alkaline phosphatase
HP:0003282
What it means
Concentration or activity of alkaline phosphatase outside the upper or lower limtis of normal in the blood circulation.
Rare diseases that can present with this3
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Low alkaline phosphatase · Low ALP
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.