Rare diseases · Sign or symptom
Corneal erosion
Damage to outer layer of the cornea of the eye
HP:0200020
What it means
An erosion or abrasion of the cornea's outermost layer of epithelial cells.
Rare diseases that can present with this21
Common30–79%
7Sometimes5–29%
13- Ablepharon macrostomia syndrome
- Acrodermatitis enteropathica
- Alport syndrome
- Apert syndrome
- Autosomal recessive generalized dystrophic epidermolysis bullosa, intermediate form
- Autosomal recessive generalized dystrophic epidermolysis bullosa, severe form
- Brittle cornea syndrome
- Congenital insensitivity to pain with severe intellectual disability
and 5 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.