Rare diseases · Sign or symptom

Confluent hyperintensity of cerebral white matter on MRI

HP:0040330

What it means

Areas of brighter than expected MRI signal in the white matter of the brain whereby individual patches run together.

Rare diseases that can present with this2

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Confluent hyperintensity of cerebral…

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.