Rare diseases · Sign or symptom
Cerebral ischemia
Disruption of blood oxygen supply to brain
HP:0002637
What it means
Restriction of arterial blood supply to the brain associated with insufficient oxygenation to support the metabolic requirements of the tissue.
Rare diseases that can present with this21
Common30–79%
7Sometimes5–29%
10- Acquired aneurysmal subarachnoid hemorrhage
- Behçet disease
- Capillary malformation-arteriovenous malformation
- Classic heparin-induced thrombocytopenia
- Craniopharyngioma
- Ebstein malformation of the tricuspid valve
- Extracranial carotid artery aneurysm
- Megalencephaly-capillary malformation-polymicrogyria syndrome
and 2 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions, and Orphanet separately records 1 disease where this sign is specifically absent. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Brain ischemia · Cerebrovascular ischemia
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.