Rare diseases · Sign or symptom
Carious teeth
Dental cavities
HP:0000670
What it means
Caries is a multifactorial bacterial infection affecting the structure of the tooth. This term has been used to describe the presence of more than expected dental caries.
It should be noted that it is not always possible to rule out environmental influences and that reports of association between hereditary diseases and susceptibility to dental caries should be regarded with caution.
In everyday care
Most people with this sign do not have a rare disease — it appears in common conditions far more often. These general reference pages cover the same topic:
Rare diseases that can present with this95
Very common80–99%
24- 49,XXXXY syndrome
- Acrofacial dysostosis, Catania type
- Anonychia with flexural pigmentation
- Aortic arch anomaly-facial dysmorphism-intellectual disability syndrome
- Arginine vasopressin resistance-intracranial calcification-short stature-facial dysmorphism syndrome
- Autosomal recessive cutis laxa type 2, classic type
- Autosomal recessive generalized dystrophic epidermolysis bullosa, severe form
- Branchioskeletogenital syndrome
- Cleidocranial dysplasia
- Corneodermatoosseous syndrome
- Craniolenticulosutural dysplasia
- Distal duplication 18q syndrome
- EEC syndrome
- Junctional epidermolysis bullosa inversa
- Microcephalic primordial dwarfism, Montreal type
- Night blindness-skeletal anomalies-dysmorphism syndrome
- Oculodentodigital dysplasia
- Odontomicronychial dysplasia
- OSLAM syndrome
- Osteogenesis imperfecta
- Otodental syndrome
- Prolidase deficiency
- Trisomy 4p syndrome
- Wrinkly skin syndrome
Common30–79%
35- 22q11.2deletion syndrome
- 48,XXXY syndrome
- 48,XXYY syndrome
- ANE syndrome
- Aspartylglucosaminuria
- Autosomal dominant Kenny-Caffey syndrome
- Autosomal recessive generalized dystrophic epidermolysis bullosa, intermediate form
- Autosomal recessive Kenny-Caffey syndrome
- Blepharo-cheilo-odontic syndrome
- Cleft lip/palate-ectodermal dysplasia syndrome
- Cockayne syndrome
- Craniofacial dysostosis-diaphyseal hyperplasia syndrome
- Diffuse cutaneous systemic sclerosis
- Distal duplication 5q syndrome
- Dyskeratosis congenita
- Ectodermal dysplasia-sensorineural deafness syndrome
- EEM syndrome
- Familial osteodysplasia, Anderson type
- Haim-Munk syndrome
- Hypohidrosis-enamel hypoplasia-palmoplantar keratoderma-intellectual disability syndrome
- Intellectual disability-muscle weakness-short stature-facial dysmorphism syndrome
- Johnson neuroectodermal syndrome
- Kindler epidermolysis bullosa
- Lacrimoauriculodentodigital syndrome
- Laryngo-onycho-cutaneous syndrome
- Metaphyseal chondrodysplasia, Spahr type
- Monosomy 18p syndrome
- Mucopolysaccharidosis type 4
- Mutilating palmoplantar keratoderma with periorificial keratotic plaques
- Pyle disease
- Radioulnar synostosis-developmental delay-hypotonia syndrome
- Recessive dystrophic epidermolysis bullosa inversa
- Regional odontodysplasia
- Rubinstein-Taybi syndrome
- THOC6-related developmental delay-microcephaly-facial dysmorphism syndrome
Sometimes5–29%
21- Albers-Schönberg osteopetrosis
- Anonychia-microcephaly syndrome
- Argininosuccinic aciduria
- B3GALT6-related spondylodysplastic Ehlers-Danlos syndrome
- Camurati-Engelmann disease
- Cockayne syndrome type 3
- Ectodermal dysplasia-skin fragility syndrome
- Floating-Harbor syndrome
and 13 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Caries · Cariosity of teeth · Dental caries · Dental decay · Early dental caries · Frequent caries · Rotting teeth · Tooth cavities
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.