Rare diseases · Sign or symptom
Calvarial hyperostosis
Overgrowth of skullcap
HP:0004490
What it means
Excessive growth of the calvaria.
The calvaria (skull cap) is made up of the frontal, occipital, right and left parietal, right and left temporal, sphenoid, and ethmoid bones, and thus comprises the upper dome-like part of the skull and does not include the lower jaw.
Rare diseases that can present with this3
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Enlargement of calvarial bones · Excessive growth of calvarial bones · Hyperostosis of calvarial bones · Hypertrophy of calvarial bones · Increased ossification of calvarial bones · Overgrowth of calvarial bones · Thick calvarial bones
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.