Rare diseases · Sign or symptom

Bifid nasal tip

Cleft nasal tip

HP:0000456

What it means

A splitting of the nasal tip. Visually assessable vertical indentation, cleft, or depression of the nasal tip.

This is a rare congenital deformity due to failure of the paired nasal processes to fuse to a single midline organ during early gestation.

Rare diseases that can present with this7

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Bifid tip of nose · Cleft tip of nose · Notched nasal tip · Notched tip of nose

Bifid nasal tip

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.