Rare diseases · Sign or symptom
Back pain
HP:0003418
What it means
An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the back.
In everyday care
Most people with this sign do not have a rare disease — it appears in common conditions far more often. These general reference pages cover the same topic:
Rare diseases that can present with this51
Common30–79%
18- Acute intermittent porphyria
- Alkaptonuria
- Autosomal dominant Emery-Dreifuss muscular dystrophy
- Autosomal recessive Emery-Dreifuss muscular dystrophy
- Cerebral autosomal recessive arteriopathy-subcortical infarcts-leukoencephalopathy
- Classical-like Ehlers-Danlos syndrome type 1
- Classic Hodgkin lymphoma
- Emery-Dreifuss muscular dystrophy
- Enthesitis-related juvenile idiopathic arthritis
- Hemorrhagic fever-renal syndrome
- Intermediate osteopetrosis
- Muscle filaminopathy
- Nail-patella syndrome
- Secondary syringomyelia
- Spinal fast-flow vascular malformation
- Spondyloepiphyseal dysplasia tarda
- Variegate porphyria
- X-linked Emery-Dreifuss muscular dystrophy
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.