Rare diseases · Sign or symptom

Attenuation of retinal blood vessels

Narrowing of blood vessels in back of eye

HP:0007843

What it means

Narrowing of the retinal blood vessels, both arterioles and venules.

Attenuation of retinal blood vessels is commonly seen in conditions with reduced photoreceptor cell metabolism and intact choroid, such as Retinitis Pigmentosa or vitamin A deficiency, or loss of inner retina, such as after central retinal artery occlusion. Narrowing may also be seen in accelerated hypertension and chronic hypertension.

Rare diseases that can present with this8

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Attenuation of retinal blood vessels

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.