Rare diseases · Sign or symptom

Aplasia/hypoplasia of the extremities

Absent/small extremities

HP:0009815

What it means

Absence (due to failure to form) or underdevelopment of the extremities.

Rare diseases that can present with this2

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Absent/underdeveloped extremities · Short or absent limbs · Shortened limbs

Aplasia/hypoplasia of the extremities

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.