Rare diseases · Sign or symptom
Anonychia
Absent nails
HP:0001798
What it means
Aplasia of the nail.
Total absence of nails.
Rare diseases that can present with this23
Very common80–99%
4Common30–79%
11- Ankyloblepharon-ectodermal defects-cleft lip/palate syndrome
- Aphalangy-hemivertebrae-urogenital-intestinal dysgenesis syndrome
- Aphalangy-syndactyly-microcephaly syndrome
- Autosomal recessive generalized dystrophic epidermolysis bullosa, severe form
- Intellectual disability-cataracts-calcified pinnae-myopathy syndrome
- Intermediate generalized junctional epidermolysis bullosa
- Late-onset junctional epidermolysis bullosa
- Localized dystrophic epidermolysis bullosa, pretibial form
- Recessive dystrophic epidermolysis bullosa inversa
- Self-improving dystrophic epidermolysis bullosa
- Severe generalized junctional epidermolysis bullosa
Sometimes5–29%
7The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Aplastic nails
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.