Familial visceral myopathy

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Familial visceral myopathy

ORPHA:2604Disease

Also called Familial hollow visceral myopathy · Hereditary hollow visceral myopathy · Megaduodenum and/or megacystis

What it is

Familial visceral myopathy is a rare hereditary myopathic degeneration of both gastrointestinal and urinary tracts that may cause chronic intestinal pseudo-obstruction. It usually presents after the first decade of life with megaduodenum, megacystis and symptoms such as abdominal distension and/or pain, vomiting, constipation, diarrhea, dysphagia, and/or urinary tract infections.

Key facts

Age of onset
All ages
Inheritance
Autosomal dominant
Classified as
Disease

Signs and symptoms

These ranges are how often a sign appears across everyone diagnosed, not a prediction for one person — most people have some of these and not others. Orphanet also records findings that are specifically absent in this disease; those are in the data but not listed here.

Gene

ACTG2Disease-causing germline mutation(s)

ICD-10 codes

K56.0filed under a broader ICD-10 category

Related health topics

Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.

Cross-references

GARD 3443MESH C562574MONDO 0016829OMIM 155310OMIM 619350UMLS C0266833

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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