Rare diseases · Sign or symptom

Amniotic constriction ring

HP:0009775

What it means

Annular constrictions around the digits, limbs, or trunk, occurring congenitally (sometimes causing intrauterine autoamputation) and also associated with a wide variety of disorders. Constrictive amniotic bands are the result of primary amniotic rupture, which can lead to entanglement of fetal tissue (especially limbs) in fibrous amniotic strands.

Pseudoainhum is a rare condition of unknown etiology that produces digital constricting rings, most commonly on the small fingers.

Rare diseases that can present with this11

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Amniotic bands · Amniotic constriction band · Congenital constriction band sequence · Pseudoainhum

Amniotic constriction ring

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.