Rare diseases · Sign or symptom

Absent lacrimal punctum

HP:0001092

What it means

No identifiable superior and/or inferior lacrimal punctum.

The lacrimal puncta (openings of the tear ducts) are normally located at the medial margin of each eyelid. The opening on the lower eyelid border is more visible than the opening on the upper eyelid border.

Rare diseases that can present with this6

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Absent lacrimal gland puncta · Absent lacrimal openings · Absent lacrimal puncta · Agenesis of the lacrimal punctum · Aplasia of lacrimal puncta · Lacrimal puncta aplasia · Lacrimal punctum, absence

Absent lacrimal punctum

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.