Rare diseases · Sign or symptom

Abnormality of the extrinsic pathway

HP:0010988

What it means

An abnormality of the extrinsic pathway (also known as the tissue factor pathway) of the coagulation cascade.

The extrinsic pathway is a protein activation cascade that contributes to blood coagulation and consists of the self-limited process linking exposure and activation of tissue factor to the activation of clotting factor X.

Part of the broader category

Abnormality of the extrinsic pathway

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.