Rare diseases · Sign or symptom

Abnormality of the alternative complement pathway

HP:0005482

What it means

A deviation in any aspect of the alternative complement pathway.

The alternative complement pathway is one of three complement pathways, which is an innate component of the immune system's natural defense against infections. The alternative complement pathway has three unique components, factor B, factor D, and properdin. {xref="PMID:16424154"}

Part of the broader category

Abnormality of the alternative complement…

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.