Rare diseases · Sign or symptom
Abnormal heart sound
HP:0031657
What it means
Any abnormal noise generated by the beating heart.
The first two heart sounds, S1 and S2, define ventricular systole. S1 comprises the closure of the mitral and tricuspid valves. S2 is produced by aortic and pulmonic valve closure.
Part of the broader category
Abnormal heart sound
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.