Rare diseases · Sign or symptom

Abnormal glomerular basement membrane morphology

HP:0033282

What it means

Any abnormal sttructure of the glomerular basement membrane.

The (GBM) is an integral component of the glomerular filtration barrier; an important and highly complex capillary wall that is exposed to mechanical forces driven by capillary hydrostatic pressure. This barrier is permeable to water and small molecules, and selectively withholds cells and macromolecules such as albumin in the circulation.

Part of the broader category

Abnormal glomerular basement membrane…

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.