Rare diseases · Sign or symptom
Abnormal circulating lactate dehydrogenase concentration
HP:0045040
What it means
A deviation from the normal serum concentration/activity of lactate dehydrogenase (LDH), which catalyzes the reduction of pyruvate to form lactate.
Rare diseases that can present with this10
Very common80–99%
4Common30–79%
4The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions, and Orphanet separately records 1 disease where this sign is specifically absent. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Abnormal circulating LDH concentration · Abnormal lactate dehydrogenase level · Abnormal LDH level · AbnormalLDH level
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.