Abnormal circulating insulin-like growth factor-binding protein acid labile subunit concentration

What it means

Any deviation from the normal concentration of insulin-like growth factor-binding protein acid labile subunit in the blood circulation.

Insulin like growth factor binding protein acid labile subunit (IGFALS; Entrez Gene ID 3483) acts in the insulin-like growth (IGF) system by binding circulating IGF1 in a ternary complex with binding protein (IGFBP)-3 to prevent IGF1 from crossing the endothelial barrier. This term refers specifically to the circulating concentration of the acid-labile subunit.

Part of the broader category

Also called: Abnormal insulin-like growth factor-binding protein complex acid labile subunit level