Rare diseases · Sign or symptom

Abnormal B cell physiology

Abnormality of B cell physiology

HP:0005372

What it means

An abnormality of the physiological functioning of B cells.

This term refers to any abnormality of the B cells, which play a role in the humoral immune response. The main functions of B cells are to produce antibodies, to perform the role of antigen presenting cells, and to develop into memory cells.

Part of the broader category

Also called: Reduced B cell function

Abnormal B cell physiology

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.