Rare diseases · Sign or symptom

2-4 toe cutaneous syndactyly

Webbed 2nd, 3rd and 4th toes

HP:0005768

What it means

A soft tissue continuity in the anteroposterior axis between the toes 2, 3, and 4.

Rare diseases that can present with this1

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Soft tissue syndactyly of toes 2, 3, and 4 · Webbed second, third and fourth toes

2-4 toe cutaneous syndactyly

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.