Non-seminomatous germ cell tumor of testis

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Non-seminomatous germ cell tumor of testis

ORPHA:363494Disease

Also called Non-dysgerminomatous germ cell tumor of testis · Testicular non seminomatous germ cell tumor · Testicular non-dysgerminomatous germ cell tumor

What it is

A form of testicular germ cell tumor occurring in the third decade of life with a usually painless unilateral mass in the scrotum or, in some cases, with gynaecomastia and/or back and flack pain. The clinical course is more aggressive than testicular seminomatous germ cell tumors with rapid involvement of blood vessels and a poorer prognosis. Histologically, the tumour can be either undifferentiated (embryonal carcinoma), differentiated (teratoma, yolk sac tumor, choriocarcinoma), or can consist of a mixture of seminomatous and nonseminomatous components.

Key facts

Prevalence
1-5 / 10 000 (lifetime, Europe)
Age of onset
Adult
Inheritance
Not applicable
Classified as
Disease

Prevalence figures describe populations, not individuals, and are often estimates from a single study. Where the figure is an incidence or a birth prevalence, it says so.

Genes

KITLGMajor susceptibility factor
SPRY4Major susceptibility factor

ICD-10 codes

C62.1filed under a broader ICD-10 category

Related health topics

Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.

Cross-references

MONDO 0006447OMIM 273300UMLS C2057625

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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