Moderate and severe traumatic brain injury

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Moderate and severe traumatic brain injury

ORPHA:90056Particular clinical situation in a disease or syndrome

What it is

A rare neurologic condition characterized by brain damage caused by an external mechanical force, with a Glasgow Coma Scale score of 9 to 12 in moderate traumatic brain injury (TBI), or 3 to 8 in severe TBI, respectively. TBI can be closed (with the dura mater remaining intact) or open (with penetration of the dura mater) and may lead to focal damage, such as cerebral contusion and hemorrhage, as well as diffuse axonal injury and secondary damage due to increased intracranial pressure. Signs and symptoms are highly variable, depending on the nature, severity, localization, and extent of the trauma.

Key facts

Prevalence
1-5 / 10 000 (Europe)
Age of onset
All ages
Inheritance
Not applicable
Classified as
Particular clinical situation in a disease or syndrome

Prevalence figures describe populations, not individuals, and are often estimates from a single study. Where the figure is an incidence or a birth prevalence, it says so.

ICD-10 codes

S06.1filed under a broader ICD-10 category
S06.2filed under a broader ICD-10 category
S06.3filed under a broader ICD-10 category
S06.4filed under a broader ICD-10 category
S06.5filed under a broader ICD-10 category
S06.6filed under a broader ICD-10 category
S06.7filed under a broader ICD-10 category
S06.8filed under a broader ICD-10 category
S06.9filed under a broader ICD-10 category

Related health topics

Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.

Benefit programs to look at

Programs whose eligibility touches the same ICD-10 categories. Eligibility is decided by the administering agency, never by this page.

Cross-references

UMLS C5681362

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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