Leiomyosarcoma of the cervix uteri

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Leiomyosarcoma of the cervix uteri

ORPHA:213807Disease

Also called Cervical leiomyosarcoma

What it is

Leiomyosarcoma of the cervix uteri is a rare, malignant mesenchymal tumor of smooth muscle origin, macroscopically appearing as a large, poorly circumscribed mass, often protruding from the cervical canal or expanding it circumferentially. The most common presenting symptoms are vaginal discharge or bleeding, pain in the lower abdomen and a bulky cervical mass. There is a reported tendency to metastatsize hematogenously, especially to the lungs, peritoneum, bones and the liver.

Key facts

Prevalence
<1 / 1 000 000 (annual incidence)
Age of onset
Adult, Elderly
Classified as
Disease

Prevalence figures describe populations, not individuals, and are often estimates from a single study. Where the figure is an incidence or a birth prevalence, it says so.

ICD-10 codes

C53.0ICD-10 uses a narrower term — shared with 10 other rare diseases
C53.1ICD-10 uses a narrower term — shared with 10 other rare diseases
C53.8ICD-10 uses a narrower term — shared with 10 other rare diseases

ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. A shared code identifies the group, not this disease — the ORPHAcode above is what identifies it.

Related health topics

Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.

Cross-references

MONDO 0016283UMLS C4289817

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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