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Start free with EleplanInfective endocarditis
ORPHA:570762Disease
Also called Infectious endocarditis
What it is
A rare infectious disease characterized by inflammation of the endocardium (including native or prosthetic heart valves and indwelling cardiac devices) mainly caused by bacterial (predominantly Staphylococcus and Streptococcus species) or rarely fungal (predominantly Candida and Aspergillus species) infections that the latter are reported to be associated with high morbidity and mortality. Major clinical features include high fever or prolonged subfebrile state, chills, diaphoresis, malaise, asthenia, arthralgia, myalgia, weight loss, headache, nausea, dyspnea, cough, heart murmurs, and petechiae of the skin. The most common complications are embolism in different organs and ischemic stroke, sepsis, heart failure, and renal failure.
Key facts
- Prevalence
- 1-9 / 100 000 (annual incidence, Europe)
- Age of onset
- All ages
- Inheritance
- Not applicable
- Classified as
- Disease
Prevalence figures describe populations, not individuals, and are often estimates from a single study. Where the figure is an incidence or a birth prevalence, it says so.
ICD-10 codes
Related health topics
Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.
Cross-references
Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.
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