Rare diseases · Sign or symptom
Anteverted nares
Nasal tip, upturned
HP:0000463
What it means
Anteriorly-facing nostrils viewed with the head in the Frankfurt horizontal and the eyes of the observer level with the eyes of the subject. This gives the appearance of an upturned nose (upturned nasal tip).
The tip of the nose is upturned and is positioned superiorly to the nasal base, allowing the nares to be easily visualized from the front. With maturation and growth of the nasal ridge and tip, the nares usually become more downwardly directed.
Rare diseases that can present with this226
Very common80–99%
75- 3M syndrome
- 3q13microdeletion syndrome
- 8p inverted duplication/deletion syndrome
- 9p13microdeletion syndrome
- Achondrogenesis
- Achondrogenesis type 1A
- Achondrogenesis type 1B
- Acrocraniofacial dysostosis
- Acromicric dysplasia
- Adenylosuccinate lyase deficiency
- Alport syndrome-intellectual disability-midface hypoplasia-elliptocytosis syndrome
- Aniridia-renal agenesis-psychomotor retardation syndrome
- Antley-Bixler syndrome
- Atkin-Flaitz syndrome
- Autosomal dominant Robinow syndrome
- Autosomal recessive cutis laxa type 2, classic type
- Autosomal recessive faciodigitogenital syndrome
- Autosomal recessive omodysplasia
- Autosomal recessive otospondylomegaepiphyseal dysplasia
- Autosomal recessive Robinow syndrome
- Barber-Say syndrome
- Brain malformation-congenital heart disease-postaxial polydactyly syndrome
- Cardiofaciocutaneous syndrome
- Carey-Fineman-Ziter syndrome
- CODAS syndrome
- Coffin-Lowry syndrome
- Cognitive impairment-coarse facies-heart defects-obesity-pulmonary involvement-short stature-skeletal dysplasia syndrome
- Congenital heart defect-round face-developmental delay syndrome
- Cooper-Jabs syndrome
- Cornelia de Lange syndrome
- Crane-Heise syndrome
- Crisponi syndrome
- C syndrome
- Desbuquois syndrome
- Distal duplication 18q syndrome
- DOORS syndrome
- Epilepsy-telangiectasia syndrome
- Epiphyseal dysplasia-hearing loss-dysmorphism syndrome
- Facial dysmorphism-anorexia-cachexia-eye and skin anomalies syndrome
- Familial intestinal malrotation
- Frontonasal dysplasia-alopecia-genital anomalies syndrome
- GAPO syndrome
- Hall-Riggs syndrome
- Hurler syndrome
- Hypomandibular faciocranial dysostosis
- Intellectual disability-short stature-hypertelorism syndrome
- Isolated rhombencephalosynapsis
- Kagami-Ogata syndrome
- Kleefstra syndrome
- Kleefstra syndrome due to 9q34 microdeletion
- Marshall-Smith syndrome
- Marshall syndrome
- Micro syndrome
- Miller-Dieker syndrome
- Monosomy 9p syndrome
- Neonatal adrenoleukodystrophy
- Neonatal hemochromatosis
- Nicolaides-Baraitser syndrome
- Osteosclerotic bone dysplasia
- Otofaciocervical syndrome
- Pitt-Hopkins syndrome
- Ptosis-upper ocular movement limitation-absence of lacrimal punctum syndrome
- Rapid-onset childhood obesity-hypothalamic dysfunction-hypoventilation-autonomic dysregulation syndrome
- Recombinant 8 syndrome
- Ring chromosome 1 syndrome
- Ring chromosome 8 syndrome
- Smith-Lemli-Opitz syndrome
- Spinocerebellar ataxia-dysmorphism syndrome
- Spondyloepiphyseal dysplasia-craniosynostosis-cleft palate-cataracts-intellectual disability syndrome
- Subaortic stenosis-short stature syndrome
- Tetrasomy 5p syndrome
- Thakker-Donnai syndrome
- Vitamin K antagonist embryofetopathy
- X small rings syndrome
- Zellweger-like syndrome without peroxisomal anomalies
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Anteverted nose · Anteverted nostrils · Nostrils anteverted · Upturned nares · Upturned nasal tip · Upturned nasal tips · Upturned nose · Upturned nostrils
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.