Rare diseases · Sign or symptom
Vesicoureteral reflux
HP:0000076
What it means
Abnormal (retrograde) movement of urine from the bladder into ureters or kidneys related to inadequacy of the valvular mechanism at the ureterovesicular junction or other causes.
Rare diseases that can present with this86
Very common80–99%
5Common30–79%
28- 8q12microduplication syndrome
- Autosomal recessive primary microcephaly
- BRESEK syndrome
- Caudal regression syndrome
- Congenital primary megaureter
- Congenital unilateral hypoplasia of depressor anguli oris
- Cornelia de Lange syndrome
- Distal 16p11.2 microdeletion syndrome
- Distal duplication 17q syndrome
- Duplication of urethra
- Exstrophy-epispadias complex
- Hand-foot-genital syndrome
- Hinman syndrome
- Hypoparathyroidism-sensorineural deafness-renal disease syndrome
- Isolated epispadias
- LUMBAR syndrome
- Melnick-Needles syndrome
- Mosaic trisomy 8 syndrome
- Neurodevelopmental disorder-craniofacial dysmorphism-cardiac defect-skeletal anomalies syndrome
- Neurodevelopmental disorder-craniofacial dysmorphism-cardiac defect-skeletal anomalies syndrome due to 9q21.3 microdeletion
- Neurodevelopmental disorder-craniofacial dysmorphism-cardiac defect-skeletal anomalies syndrome due to a point mutation
- Oculoauriculovertebral spectrum with radial defects
- Posterior urethral valve
- Renal coloboma syndrome
- Renal hypoplasia, bilateral
- Syndactyly-telecanthus-anogenital and renal malformations syndrome
- Urofacial syndrome
- X-linked intellectual disability, Nascimento type
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Ureteral reflux · Ureteric reflux · Vesico-ureteral reflux · Vesicoureteric reflux · VUR
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.