Congenital Epstein-Barr virus infection

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Congenital Epstein-Barr virus infection

ORPHA:70596Disease

Also called Antenatal EBV infection · Antenatal Epstein-Barr virus infection · Congenital EBV infection · Mother-to-child transmission of Epstein-Barr virus infection

What it is

A rare infectious disease that causes no clinical manifestations in the majority of infants. Indeed, the occurrence of congenital infection with EBV has never been demonstrated conclusively and must be very rare. One case has been reported to present after birth, multiple congenital anomalies (micrognathia, cryptorchidism, central cataracts), dystrophy, generalized hypotonia, hepatosplenomegaly, diffuse petechiae and hematomas and multiple areas of metaphysitis of the long bones at birth. A low birth weight was also reported. No specific follow-up of the fetus is recommended following maternal EBV primary-infection.

Key facts

Age of onset
Infancy, Neonatal
Inheritance
Not applicable
Classified as
Disease

ICD-10 codes

P35.8filed under a broader ICD-10 category — shared with 3 other rare diseases

ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. A shared code identifies the group, not this disease — the ORPHAcode above is what identifies it.

Related health topics

Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.

Cross-references

MONDO 0019094UMLS C4274357

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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