Brachydactyly type E

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Brachydactyly type E

ORPHA:93387Malformation syndrome

What it is

Brachydactyly type E (BDE) is a congenital malformation of the digits characterized by variable shortening of the metacarpals with more or less normal length phalanges, although the terminal phalanges are often short.

Key facts

Age of onset
Antenatal
Inheritance
Autosomal dominant
Classified as
Malformation syndrome

Signs and symptoms

These ranges are how often a sign appears across everyone diagnosed, not a prediction for one person — most people have some of these and not others. Orphanet also records findings that are specifically absent in this disease; those are in the data but not listed here.

Genes

HOXD13Disease-causing germline mutation(s)
PTHLHDisease-causing germline mutation(s) (loss of function)

ICD-10 codes

Q73.8filed under a broader ICD-10 category — shared with 25 other rare diseases

ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. A shared code identifies the group, not this disease — the ORPHAcode above is what identifies it.

Cross-references

GARD 987MESH C566194MONDO 0019677OMIM 113300OMIM 613382UMLS C4315392

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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